Pharmaceutical Chemistry Department

EQUIPMENT

Chromatography and Electrophoresis


  • Protein Simple iCE3 (pictured)
  • Thermo UHPLC (pictured with UV-visible and fluorescence detectors and autosampler)
  • Agilent UHPLC and Shimadzu HPLC (4) (with UV, Fluorescence, Light Scattering and RI detectors available)
  • Convergent Bioscience iCE280 Fast IEF Analyzer
  • Amersham Pharmacia Viotech AKTA FPLC System
  • Alpha Imager Gel Imaging System

Mass Spectrometry

  • Thermo LTQ XL Mass Spectrometer w/Thermo UHPLC (Fluorescence and UV detection) (pictured)
  • Agilent TOF Mass Spectrometer w/Agilent HPLC
  • Agilent CE-SDS and IEF system for in-line or off-line use w/TOF

Spectroscopy


 

  • Applied Photophysics Chirascan-plus (3) (pictured)
  • Brucker Vertex 70 FTIR Spectophotometer (pictured0
  • PTI Steady-State and Lifetime Fluorometer (3) (pictured)
  • Agilent 8453 UV-Vis Spectrophotometer (2)
  • Bruker Tensor 27 FTIR Spectrometer
  • Cary 100 Bio UV-Visible Spectrophotometer
  • Fluorescence Innovations Lifetime Fluorometer (384 well plate)

Calorimetry

  • MicroCal High Throughput Differential Scanning Calorimeter (2) (pictured)
  • MicroCal Auto-Isothermal Titration Calorimeter (ITC)
  • TA Instruments Q100 Differential Scanning Calorimeter and Q50 Thermogravimetric Analyzer

Light Scattering and Analytical Ultracentrifugation

  • Wyatt DynaPro Plate Reader (pictured)
  • Wyatt Calypso Gradient Mixer (for CG MALS capabilities) (pictured)
  • Beckman-Coulter ProteomeLab XL-1 Analytical Ultracentrifuge (pictured)​
  • Wyatt Dawn Heleos II Multi-Angle Light Scattering Detector (batch measurements and in-line HPLC detection) ​
  • Brookhaven ZetaPALS Zeta Potential Analyzer

Immunoassays


  • Forte Bio Octet Red96 multichannel Bio-Layer Interferometry System (pictured)
  • BioTek automated plate washer for ELISA (pictured)
  • SpectraMax M5 microtiter plate reader for ELISA
  • Forte Bio BLITZ single channel Bio-Layer Interferometry System

Live Virus Potency Measurements (in BSL-2 Labs)


  • QuantStudio TM 7 Flex Real-Time PCR System (3) (pictured)
  • Nikon Eclipse Ti-E Fluorescence Microscope (pictured)​
  • SpectraMax M3 plate reader
  • Separate virus and cell culture labs with incubators, microscopes, biosafety cabinets

Live Virus Biophysical and Particle Characterization (in BSL-2 Lab)

  • Nanosight LM-10HS nanoparticle tracking system (pictured)
  • Protein Simple MFI DPA-4200
  • Agilent 8453 UV-Vis spectrometer
  • Jasco J-810 Circular Dichroism Spectropolarimeter
  • PTI Steady-State and Lifetime Fluorometer
  • Beckman-Coulter Benchtop and floor preparative ultracentrifuges

Lyophilization Lab

  • FTS Lyo Star II (pictured)
  • FTS Virtis Advantage Plus-EL Benchtop Lyophilizer (in BL2 labs)
  • TA Instruments Q100 Differential Scanning Calorimeter and Q50 Thermogravimetric Analyzer (for Tg and Tg’)
  • Karl Fisher titrator (Oven method)
  • Karl Fisher titrator (Dry methanol method)

Pharmaceutical properties 

  • Rheosense m-VROC viscometer
  • Anton Paar Viscometer
  • Anton Paar High Sensitivity Density Meter (2)
  • Wyatt Optilab rEX differential refractometer
  • Precision Systems Osmette II osmometer

785-864-3356
Vaccine Analytics and Formulation Center
2030 Becker Dr.
Lawrence, KS 66047