Live Vaccines and Vectors

Hickey JM, Jacob SI, Tait AS, Vahid FD, Barritt J, Rouse S, Douglas A, Joshi SB, Volkin DB, Bracewell DG “Measurement of adenovirus-based vector heterogeneity” J. Pharm Sci 112(4):974-984 (2023)

Gupta V, Antunez LR, Saleh-Birdjandi S, Kumru OS, Pospisil R, Lilja A, Fuhrmann G, Smith L, Volkin DB, Joshi SB. “Development of a high-throughput RT-PCR based viral infectivity assay for monitoring the stability of a replicating recombinant Lymphocytic Choriomeningitis viral vector” J Virol Methods 301:114449 (2022)

Pullagurla SR, Kumar P, Ogun O, Kumru OS, Hamidi A, Hoeksema F, Yallop C, Bines JE, Volkin DB, Joshi SB. “Modeling the long-term 2-8 °C stability profiles of a live, rotavirus vaccine candidate (RV3-BB) in various liquid formulations via extrapolations of real-time and accelerated stability data” Biologicals 75:21-28 Epub (2022)

Wan Y, Gupta V, Bird C, Pullagurla S, Fahey P, Forster A, Volkin DB, Joshi SB. “Formulation Development and Improved Stability of a Combination Measles and Rubella Live-Viral Vaccine Dried for use in the NanopatchTM Microneedle Delivery System ” Human Vaccines and Immuotherapeutics  17(8):2501-2516 (2021)

Kumar P, Pullagurla SR, Patel A, Shukla RS, Bird C, Kumru OS, Hamidi A, Hoeksema F, Yallop C, Bines JE, Joshi SB, Volkin DB.  “Effect of formulation variables on the stability of a live, rotavirus (RV3-BB) vaccine candidate using in vitro gastric digestion models to mimic oral delivery” J Pharm Sci 110(2):760-770 (2021)

Kumar P, Shukla R, Patel A, Pullagurla S, Bird C, Ogun O, Kumru OS, Hamidi A, Hoeksema F, Yallop C, Bines JE, Joshi SB, Volkin DB. “Formulation Development of a Live Attenuated Human Rotavirus (RV3-BB) Vaccine Candidate for use in Low and Middle-Income Countries” Human Vaccines and Immunotherapeutics  17(7):2298-2310 (2021)

Kumru OS, Saleh-Birdjandi S, Antunez LR, Sayeed E, Robinson D, van den Worm S, Diemer GS, Perez W, Caposio P, Früh K, Joshi SB, Volkin DB “Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine” J. Pharm Sci. 37(44):6696-6706 (2019)

Hamidi A, Hoeksema F, Velthof P, Lemckert A, Gillissen G, Luitjens A, Bines JE, Pullagurla SR, Kumar P, Volkin DB, Joshi SB, Havenga M, Bakker WAM, Yallop C “Developing a manufacturing process to deliver a cost effective and stable liquid human rotavirus vaccine” Vaccine 39(15):2048-2059 (2021)