New Vaccine Platforms (viral vectors; mRNA-LNPs)

Kumar P, Holland DA, Secrist K, Taskar P, Dotson B, Saleh-Birdjandi S, Adewunmi Y, Doering J, Mantis NJ, Volkin DB, Joshi SB. "Evaluating the compatibility of new recombinant protein antigens (trivalent NRRV) with a mock pentavalent combination vaccine containing whole-cell pertussis: analytical and formulation challenges" Vaccines In Press (2024)

Kumar P, Wang M, Kumru OS, Hickey JM, Sanmiguel J, Zabaleta N, Vandenberghe LH, Joshi SB, Volkin DB. "Correlating physicochemical and biological properties to define critical quality attributes of a rAAV vaccine candidate" Molecular Therapy-Methods & Clinical Development 30: 103-121 (2023)

Hickey JM, Jacob SI, Tait AS, Vahid FD, Barritt J, Rouse S, Douglas A, Joshi SB, Volkin DB, Bracewell DG “Measurement of adenovirus-based vector heterogeneity” J. Pharm Sci 112(4):974-984 (2023)

Gupta V, Antunez LR, Saleh-Birdjandi S, Kumru OS, Pospisil R, Lilja A, Fuhrmann G, Smith L, Volkin DB, Joshi SB. “Development of a high-throughput RT-PCR based viral infectivity assay for monitoring the stability of a replicating recombinant Lymphocytic Choriomeningitis viral vector” J Virol Methods 301:114449 (2022)

Blenke, EO, Ornskov E, Schoneich C, Nilsson GA, Volkin DB, Mastrobattista E, Almarsson O, Crommelin DJA. "The storage and in-use stability of mRNA Vaccines and Therapeutics: Not a cold case" J. Pharm Sci.112(2):386-403 (2023)

Kumru OS, Saleh-Birdjandi S, Antunez LR, Sayeed E, Robinson D, van den Worm S, Diemer GS, Perez W, Caposio P, Früh K, Joshi SB, Volkin DB “Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine” J. Pharm Sci. 37(44):6696-6706 (2019)

Crommelin DJA, Volkin DB, Hoogendoorn KH, Lubiniecki AS, Jiskoot W. “The science is there: key considerations for stabilizing viral vector-based Covid-19 vaccines” J. Pharm Sci. 110(2):627-34 (2020)

Crommelin DJA, Anchordoquy TJ, Volkin DB, Jiskoot W, Mastrobattista E. “Addressing the cold reality of mRNA vaccine stability” J. Pharm Sci. 110(3):997-1001 (2020)